Endocrine Abstracts

Background and aim: The management of Congenital Growth hormone deficiency (CGHD) is based on hormonal substitution with recombinant GH. The stature prognosis may be affected by several clinical, genetic, and therapeutic factors. This study aims to assess the predictive clinical factors of stature gain in CGHD-treated patients.Patients and Methods: We conducted a retrospective study (1991–2019) at the Endocrinology department of Hedi Chaker Universi...

Background and aim: Disorders of the development of the pituitary gland could result in some forms of Congenital Growth hormone deficiency (CGHD). This study aims to assess the morphological abnormalities of the pituitary gland in patients with CGHD.Patients and Methods: We conducted a retrospective study (1991–2019) at the Endocrinology department of Hedi Chaker University Hospital, Sfax, Tunisia. We involved 87 patients diagnosed with CGHD, whose ...

Objective: To describe the radiological features of non-functioning pituitary adenomas (NFPA) at diagnosis.Patients and methods: A retrospective descriptive study of 35 patients followed for NFPA between 2000 and 2022. A pituitary magnetic resonance imaging (MRI) scan was performed in all patients.Results: The mean age was 52.1±11.4 years with a male predominance (61.3%). Pituitary tumor syndrome was the main reason for consul...

Introduction: Prolactinomas in men are rare but are characterised by their giant and invasive nature. They present with signs of hypogonadism and mass effect. The aim of this study is to clarify the clinical, biological, radiological and therapeutic features of Prolactinomas in men.Patients and methods: Retrospective descriptive study including 27 adult males with a prolactin pituitary adenoma hospitalized in the endocrinology department of the Hedi Chak...

IntroductionSubclinical Cushing’s syndrome (SCS) is an endocrine disorder characterized by an autonomous cortisol secretion in patients bearing adrenal adenomas in the absence of specific signs of hypercortisolism. The cortisol excess is known to be associated with metabolic comorbidities such as obesity, hypertension, glucose intolerance, and dyslipidemia increasing the incidence of cardiovascular events. The objective of this study was to describe...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...

IntroductionMitochondrial diseases are a clinically heterogeneous group of disorders that arise as a result of dysfunction of the mitochondrial respiratory chain.it is genetically heterogeneous diseases characterized by multisystem involvement. Thus, its clinical description is incomplete. The aim of this case report is to highlight the association between mitochondrial diabetes and severe hypertriglyceridemia. In this study, we describe the case of a 22...

IntroductionObesity is recognized to be one of the greatest public health problems worldwide. In addition to physical health problems, obesity is also linked to an increased risk of mental health disorders such as anxiety. The objective of this study was to determine the prevalence of anxiety in obese adults and the factors associated with anxiety in this population.MethodsWe conducted a cross-sectional study...

BackgroundIt’s well known that smoking and diabetes are direct causes for serious health problems such as cancer, and atherosclerosis. It is suggested that smoking indirectly leads to atherosclerosis by influencing nutrient intakes as smokers tend to eat more fat and carbohydrates and less mono unsaturated fats and fiber than non-smokers. But no studies assessed the impact of tobacco on nutrition in diabetic patients.Aim<p...

Introduction Hypothyroidism (HT) is widespread in all age groups particularly within the increasing elderly population while its diagnosis is challenging owing to extremely varied and atypical symptoms. The objective of this study is to outline the clinical and biochemical features of HT and determine its main etiologies in a geriatric population. Methods We reviewed the medical charts of 53 patients aged 65 ...